International Journal of Clinical and Experimental Physiology

Yoga Therapy: Concept, Principle, Clinical Applications and Future Perspectives

2026-03-17T09:10:37+00:00

Yoga therapy has emerged as a structured, individualized therapeutic modality derived from traditional yogic practices and adapted for contemporary healthcare. Unlike general yoga practice aimed at health promotion and disease prevention, yoga therapy involves the targeted application of specific yogic techniques for the management of defined clinical conditions. This review-style editorial examines the conceptual framework, principles, techniques, and clinical applications of yoga therapy, highlighting its holistic foundation and integrative potential. The relevance of yoga therapy within modern medicine and its future prospects in evidence-based healthcare are also discussed.

The Role of Yoga Therapy in Tuberculosis Recovery and Management: A Review

2026-03-17T09:16:10+00:00

Tuberculosis (TB) remains a global health burden, with prolonged treatment causing physical and psychological strain. Complementary therapies, such as yoga, may enhance recovery and management of tuberculosis; however, a synthesis of evidence is lacking. This review was conducted on clinical trials retrieved from PubMed, Scopus, and the Cochrane Library (2000– 2024) using the following keywords: "yoga," "tuberculosis," "pulmonary rehabilitation," and "mind-body therapy." Clinical trials, observational studies, and mechanistic reports were included in the analysis. Yoga improves lung function, reduces stress and oxidative stress, and alleviates anxiety/ depression. Trials show adjunctive yoga accelerates sputum conversion and improves quality of life. Yoga therapy is a promising adjunct for TB recovery and management, but larger RCTs are needed to standardize protocols.

Exogenous Nitric Oxide Plays Important Roles in Wound Healing and has an Antibacterial Effect

2026-03-17T09:22:47+00:00

Background and Aim: While air plasma has been widely used in biomedical or clinical applications, nitric oxide produced with plasma is thought to play important roles and be significant in biological activities. Our aim is to elucidate the role of exogenous nitric oxide in wound healing and antibacterial effect. Methods: 140 Wistar rats weighing 180 to 230 g were used. They were injured and irradiated by NO-containing plasma. Results: Wound healing was promoted in case of NO-containing plasma therapy. Conclusion: Exogenous nitric oxide prompts wound healing and has an antibacterial effect.

Effects of Combined Action of Valproate and Ginkgo biloba on Cognitive Function in Penicillin-Induced Developmental Epilepsy of Rat

2026-03-17T09:30:09+00:00

Background and Aim: The aim of this study is to demonstrate the effect of combined action of Valproate and Ginkgo biloba on cognitive function in penicillin-induced developmental epilepsy of rat. Methods: Penicillin-induced developmental epilepsy in adolescence rat was established by intraperitoneal injection of penicillin diluted in saline as previously reported. Rats were assigned to 3 groups: Control group (CG), Penicillin-induced seizures group (MG) and Combination group of Valproate and Ginkgo biloba (V+G). The effect of combination of Valproate and Ginkgo biloba was evaluated through the test of water maze. Results: The present study demonstrated that the combination of Valproate and Ginkgo biloba improved cognitive dysfunction and resulted in higher therapeutic efficacy. Conclusion: Our data provide that combination of Valproate and Ginkgo biloba may be useful for treatment of developmental Epilepsy.

To Explore the Positive Adaptive and Transformative Changes in the Health System and Community During the COVID-19 Pandemic in Puducherry

2026-03-17T09:35:48+00:00

Background and Aim: The COVID-19 pandemic placed substantial pressure on health systems, but it also created opportunities for positive organisational change. While most studies from India have focused on challenges, limited evidence describes the beneficial adaptations that strengthened routine systems during the pandemic. This study aimed to explore the positive adaptive and transformative changes in the health system and community during COVID-19 in Puducherry. Methods: A qualitative study was conducted using a phenomenological approach. Eight key informant interviews and three focus group discussions were carried out across primary, secondary and tertiary care facilities in Puducherry in 2021. Participants were purposively selected using maximum variation sampling. Data were collected using semi-structured guides mapped to health system building blocks, audio-recorded, transcribed verbatim and analysed using a hybrid inductive–deductive approach guided by the Health Systems Dynamics Framework. Themes were validated through investigator triangulation and participant confirmation. Results: Ten major thematic areas emerged: leadership and governance, human resources, infrastructure and supplies, financing, knowledge and information, service delivery, population behaviour, context, values and principles, and outcomes. Participants described stronger leadership presence, improved teamwork, rapid decision-making and effective intersectoral collaboration. Infrastructure and digital platforms expanded quickly, including oxygen plants, diagnostics, telemedicine and digital documentation. Service delivery became flexible through home-based care, teleconsultation and vaccination outreach. Community trust in government services improved, and adherence to preventive behaviours increased. Conclusion: The COVID-19 pandemic impelled positive changes in Puducherry’s health system, including stronger leadership, better coordination, improved infrastructure, digitalisation, and increased community engagement. Sustaining these improvements can strengthen routine services and emergency preparedness.

Effect of Calcium Alginate Stopper on Persistent Air Leakage in the Lung of Rats

2026-03-17T09:43:11+00:00

Background and Aim: A number of adverse consequences of Persistent Air Leakage (PAL) account for the morbidity and mortality associated with this condition. Calcium Alginate is known as an effective and bioactive occlusion material, but the effect of Calcium Alginate stopper on air leakage has not yet been investigated in vivo. Here, we aim to examine the efficiency of Calcium Alginate stopper in the prevention of air leakage in the lung of rats. Methods: A total of 24 rats were included in the study. Comparable tissue injury was induced in all groups by performing right anterior thoracotomies. The control group received no treatment at the injury site, the standard surgery group underwent conventional suturing, and the experimental group was treated with a calcium alginate stopper. Results: At a positive airway pressure of 5 cmH₂O, air leakage was detected in the isolated lungs of the control group but was absent in both the standard surgery and study groups. The mean airway pressure required to induce air leakage was 6.1 ± 0.5 cmH_₂O in the control group, 17.3 ± 3.1 cm H_₂O in the standard surgery group, and 21.6 ± 3.5 cmH₂O in the study group, respectively. Conclusion: The calcium alginate stopper effectively prevented air leakage in rat lungs, with no significant difference observed when compared with the standard surgery group.